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CALCIUM RELEASE-ACTIVATED CALCIUM CHANNELS
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DeCS
Descriptor
English
:
Calcium Release Activated Calcium Channels
Descriptor
Spanish
:
Canales de Calcio Activados por la Liberación de Calcio
Descriptor
Portuguese
:
Canais de Cálcio Ativados pela Liberação de Cálcio
Synonyms
English
:
CRAC Channels
Calcium Release Activated Channels
Calcium Release-Activated Calcium Channels
Calcium Release-Activated Channels
Tree Number:
D12.776.157.530.400.150.740
D12.776.543.550.450.150.740
D12.776.543.585.400.150.740
Definition
English
:
Specialized
calcium channels
that localize to the ENDOPLAMSIC
RETICULUM
and
PLASMA
MEMBRANE. They contain the pore subunit
ORAI1 PROTEIN
which is activated by
STROMAL INTERACTION MOLECULES
upon intracellular
calcium
depletion.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56582
Unique Identifier:
D000071739
Occurrence in VHL
:
Similar:
DeCS